Gradual taper of dose The Approach For patients who want to find the lowest effective dose or to discontinue completely, a gradual taper means stepping the GLP-1 dose down in small, planned increments (typically using the same titration steps as initiation, but in reverse) to test whether benefit can be maintained with less medication or none at all
Retatrutide is an investigational triple agonist peptide targeting GIP, GLP-1, and glucagon receptors, currently under clinical development for the management of obesity and type 2 diabetes
E., Wolski, K., Feng, Q., Gyongyosi, M., Lscher, T
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But until FDA review is complete, questions remain about safety, efficacy, quality oversight, and appropriate use
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