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As insufficient supply problems persist, the European Medicines Agency considers this a major public health concern. It has advised medical professionals to only prescribe these medicines for their licensed uses and that it is necessary to strictly adhere to national clinical practice guidelines

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A modest, flexible deficit of approximately 250500 kcal per day, combined with regular meals and adequate protein and fibre, is safer than aggressive restriction for those managing binge tendencies

A physician review of nutrition and activity can help during plateaus

Ding J, Wang K, Liu W, She Y, Sun Q, Shi J, et al