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A linear regression analysis was used to assess the association between metabolites (glutamate and GSH), and both time to response, and social functioning (Hypotheses 1 and 3)

LC-MS/MS instrumentation and conditions LC-MS/MS analysis was performed using a Waters UPLC instrument with an Acquity TM binary solvent manager, Acquity TM 4-position heated column manager and 2777 Ultra High Pressure Autosampler coupled to a Xevo-TQ MS triple quadrupole mass spectrometer (Waters Ltd, Herts, UK) with an electrospray ionisation (ESI) source

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The patients age helps clarify the cause of the ingestion