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While generally safe and well-tolerated, the drugs triple-action mechanism introduces specific challenges for titration and patient management

The information presented herein is accurate to the best of the author's knowledge at the time of publication

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Code availability Code is available on GitHub ( for a package we generated that includes detailed documentation, which explains the models architecture, data preprocessing steps and how to run the code

Doses are usually low and delivered in short pulses or continuous infusion based on effect needed, which makes stimulation targeted and controllable compared to more general agents

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