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The main hormonal alterations found in PCOS include increased luteinizing hormone/follicle stimulating hormone (LH/FSH) ratio, hyperandrogenism, and insulin resistance, with consequent compensatory hyperinsulinemia, occasionally independent of body weight [2, 8]

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Endocrinology (2009) 150:117481.10.1210/en.2008-1221 99 AbbottCRMonteiroMSmallCJSajediASmithKLParkinsonJRet alThe inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway