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49 Further evaluation on a double-blind, randomized phase 1 clinical trial in 98 patients with T2DM on current management with metformin revealed that Danuglipron was generally well tolerated and associated with minimal side effects such as nausea, dyspepsia, and vomiting comparable with the ones observed with the use of injectable GLP-1RA

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However, they pose three significant risks for athletes: hypovolemia/dehydration from osmotic diuresis, an increased risk of hypoglycemia when used with insulin or sulfonylureas, and the potential for euglycemic DKA (74)

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[84] found that low serum selenium levels correlated with enlarged thyroid volume and increased nodules in moderately iodine-deficient Danish areas, both before and after iodine fortification [84]