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Using NanoBiT complementation, we found subtle differences in GLP-1R coupling to both G s and -arrestin-2 between exendin-4 and lixisenatide, although it is not clear whether this is sufficient to explain the significant differences in potency for cAMP signalling

Microglia and macrophages in brain homeostasis and disease

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Liraglutide is a daily injectable medication used for long-term weight management