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When studied together, the effect appears additive rather than redundant

While comprehensive national data is limited, GLP-1 receptor agonists represent a major therapeutic class for type 2 diabetes, with the majority of current users having diabetes as their primary indication

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Common Zepbound side effects The most common side effects of Zepound include nausea, diarrhea, vomiting, constipation, abdominal pain, indigestion, and reflux reported in over 5% of patients treated with the drug in clinical studies

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By blocking opioid receptors on the POMC neurons, feedback inhibition is prevented further increasing POMC activity