Figure 16: Painting of Professor John C Brown (19382016) by his grandson, Matthew T Kieffer, credit: Kieffer
If you can get away with a microdose and achieve your physical goals, then by all means microdose, says Seltzer
However, their precise role within the pancreas remains largely unexplored
The FDA has received reports of dosing errors associated with compounded GLP-1s, including patients accidentally taking too much or too little and experiencing complications such as fainting, dehydration and severe gastrointestinal symptoms
At the 4mg/week dose level, a single 10mg vial supplies 2.5 weeks of research
Several next-generation compounds are progressing through clinical development that may offer improved efficacy, better tolerability, or lower production costs