Notably, bone marrow lipid content is markedly increased in precursor MM states (MGUS and SMM) compared to healthy controls (Panaroni et al., 2022)
GST catalyzes the conjugation of cytotoxic agents to glutathione (-glutamyl-cysteinyl-glycine), producing less reactive chemical species
For example, mixing 10 ml of bacteriostatic water into a 5 mg vial produces a 0.5 mg/ml solution so a "25-unit dose" on a U-100 syringe now delivers only 0.125 mg, half the intended amount
Physiological Expectations for Low-Dose Therapy Low-dose HGH therapy, which is 1 to 2 IU per day, is often used for anti-aging and wellness
A 2020 study of "wellness" B12 injections in non-deficient adults found no improvement in energy, mood, or cognitive function versus placebo at 4 weeks (Wolffenbuttel et al., Nutrients , 2020)
The maximum dosage is 15 mg once a week