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Overloaded iron generates a large amount of ROS by inducing the Fenton reaction, forming an imbalance between antioxidants and leading to oxidative stress reactions such as cellular oxidative damage [83]

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2013;8:e71568

Thus, although it is likely that endogenous GLP-1 signals via a vagal gutbrain axis to lower meal size, the impact of this signaling pathway on overall energy homeostasis may be limited

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