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In peer-reviewed animal work the concrete numbers are oral doses of roughly 1.442.88 mg/kg given daily to APP/PS1 Alzheimer-model mice over about three months [3] , and low-mg/kg dosing that reversed scopolamine-induced deficits in rodents [1]

For example, the 6H8 ( 61 ) fragment, obtained through NMR screening from the Maybridge library, may act as a covalent warhead targeting the pathological substrate APP of -secretase, thereby hindering A production

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