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Immune checkpoint inhibitors (ICIs) are a class of anticancer drugs known as monoclonal antibodies that target receptors like anti-programmed death 1 (anti-PD-1), anti-programmed death-ligand 1 (anti-PDL-1) and the anti-cytotoxic T-lymphocyte-associated antigen 4 (anti-CTLA-4)

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To recognize potential patterns, we utilized Principle Component Analysis (PCA) and Orthogonal Partial Least-Squares-Discriminant Analysis (OPLS-DA)

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