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The core concept of all these studies is to pair an anorectic agent (GLP-1 or GLP-1/GIP) with an anabolic agent, such as anti-myostatin or bimagrumab

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J Gastroenterol Hepatol 13:301304

In summary: For guys who choose to take charge of their health, semaglutide offers a revolutionary method of weight loss

Semaglutide is a once-weekly GLP-1 receptor agonist developed by Novo Nordisk and approved as Ozempic for type 2 diabetes, Wegovy for chronic weight management, and Rybelsus as an oral tablet

Variants in the GLP-1 receptor gene (rs6923761), FTO gene (rs9939609), and MC4R gene (rs17782313) can support a more informed conversation with your provider about your baseline appetite sensitivity and potential durability of weight loss if treatment is paused