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Analog 52 was identified as the most active analog based on the PPRE relative activities

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The subcutaneous route of administration allows for self-injection, typically in the abdomen, thigh, or upper arm

Lysine Catabolism via the Saccharopine Pathway There are several, at least three, pathways for lysine catabolism but the primary pathway utilized within the liver of humans is one that begins with the formation of an adduct between lysine and 2-oxoglutarate (-ketoglutarate) called saccharopine

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