In plain terms, CagriSema reduced weight effectively, but it did not match the incumbent in a head-to-head setting
Having this insight upfront means you're less likely to waste money on a treatment path that doesn't align with your biology, effectively paying for itself within 23 months through faster, more efficient weight loss
Diabetes Metab Syndr Obes 12, 22212236
Constipation relief is the fastest: most people notice a difference within 24-72 hours of their first dose
The phase 3 TRIUMPH-4 data showed these rates at 9 mg and 12 mg doses respectively: Nausea: 38.1% and 43.2% (vs 10.7% placebo) Diarrhea: 34.7% and 33.1% (vs 13.4% placebo) Constipation: 21.8% and 25.0% (vs 8.7% placebo) Vomiting: 20.4% and 20.9% (vs placebo) These numbers are higher than cagrilintide monotherapy across the board
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