These are the newer GLP-1 therapies that have shown superior results to prior therapies in lowering A1C (blood sugar) levels of diabetics and helping those who are obese lose weight
Key findings: 12 mg dose: Average weight loss of 24.2% of body weight (approximately 58 lbs for a 240 lb individual) 8 mg dose: Average weight loss of 22.8% 4 mg dose: Average weight loss of 17.0% Placebo: Average weight loss of 2.1% Over 90% of participants receiving the 8 mg or 12 mg dose lost at least 10% of body weight Over 75% of participants at the highest dose lost at least 20% of body weight Significant improvements in waist circumference, blood pressure, and lipid profiles were observed across dose groups Phase 2 Trial in Type 2 Diabetes A separate phase 2 trial evaluated retatrutide in adults with type 2 diabetes and obesity (Rosenstock et al., Lancet , 2023)
Ozempic Prescribed for Weight Loss (Off-Label): Confirm payer coverage for weight loss before prescribing Ozempic for obesity alone
International Journal of Cosmetic Science, 44(2), 112120
You can't out-medicate a terrible diet, inconsistent training, chronic sleep deprivation, or unmanaged stress
Genetics can influence how you respond to the drug
