The studies reported improvements in spasticity and athetosis [126, 127, 132, 143, 147], as well as gait [129] and respiration [137]
Cardiovascular complicationsincluding myocardial hypertrophy, arrhythmias, endothelial dysfunction, and accelerated atherosclerotic processesappear to represent the most clinically significant outcomes and may persist in some individuals even after cessation of steroid use
The 28-day standard applies to formulations with minimal preservatives, while those with higher benzyl alcohol concentrations may extend to 6090 days
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In our analysis, significant weight regain was observed only in the lower baseline BMI subgroups which did not conform to the common understanding, possibly because the enrolled patients were more severely obese and then not well differentiated by the BMI cutoff point, and the limited data in the analysis also reduced the confidence of the result