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Moreover, dapagliflozin markedly alleviates neuronal oxidative stress, tau phosphorylation and amyloid- production due to the ability to counteract neuronal apoptosis and upregulating glial cell-derived neurotrophic factor (Arab et al., 2021)

Since that time, more investigations have been carried out by a network of collaborators, which leads to the perspective in this manuscript that while PBM has a significant effect on TBI, modifications of the underlying cellular mechanisms by adjusting certain parameters can lead to better outcomes

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