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It is contraindicated in patients taking monoamine oxidase inhibitors (MAOIs) or with hypersensitivity to amphetamine products

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Future research should focus on identifying pain-specific biomarkers, refining diagnostic criteria, and integrating multi-omics data and neuroimaging techniques to better distinguish pain mechanisms in IBS-C versus FC and develop more precise, patient-centered interventions

Total-Body PET: Maximizing Sensitivity to Create New Opportunities for Clinical Research and Patient Care

Further, access issues, market shortages, insurance coverage, and the ethics of off-label use were found to be discussed