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Retatrutide has a half-life of approximately 6 days, which supports the once-weekly dosing schedule

There are some serious risks associated with the GLP-1 receptor agonists

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In order to maintain the bile acid pool, therefore, the amount of bile acid excreted is almost equal to the amount newly synthesized by the liver

If this happens, the integrity of the compound is compromised, and for research purposes, it should ideally be discarded to avoid skewed results

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