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Mechanism of Action: 2 adrenoreceptor agonist Peripheral : 2 agonists can directly cause arterial vasoconstriction , which can cause an initial phase of hypertension , before centrally mediated effects predominate, resulting in reduced sympathetic outflow from the CNS, which results in both bradycardia and hypotension (Malayala et al, 2022

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3k, top row), suggesting that GSH-mee can rescue the inhibition of GPX4

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doi:10.1007/s00394-014-0706-z [2] Cui X, Mi T, Xiao X, et al