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Chang YF, Gao XM

Several studies have shown that astrocytes can be genetically reprogrammed to adopt neuronal identities and restore neural circuitry 25

Improper solvent selection, incorrect volumes, insufficient buffering, or low-grade reagents may result in clumping, cloudiness, gelling, aggregation, or incomplete dissolution

Intriguingly, a recent randomised controlled trial found that metformin significantly improved depressive symptoms in patients with treatment-resistant bipolar depression [134]

Access to these innovative therapies should be expanded in low- and middle-income countries through policy inclusion, generic drug development, and integration into national chronic disease management programs

Some studies show up to 27% life extension