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Others suffer from gastrointestinal issues such as loss of appetite and constipation

In recent works, the study demonstrated that GCH1/ BH4 pathic enzyme dihydrofolate reductase (DHFR) could inhibit ferroptosis by generating BH4, so decrease in DHFR activity reduces BH4 content to enhance lipid peroxidation and sensitizes cells to ferroptosis (Lu et al., 2024), but the detail process is still unknown (Figure 1)

The field is expanding rapidly, and the complete peptide list continues to grow as new compounds are identified and characterized

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The pepper gene CaBPR1 , which encodes basic PR1, was strongly induced by ethephon, wounding, and virus infection