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In a landmark human trial comparing topical GHK-Cu to vitamin C and retinoic acid (tretinoin), GHK-Cu produced measurable collagen increases in 70% of study volunteers outperforming both comparator treatments (Abdulghani et al., 1998)

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Wang, J., Li, M., Geng, Z., Khattak, S., Ji, X., Wu, D., & Dang, Y