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H.HojrupP.HolstJ

March 2022

LeanGBB drives thermogenesis through the carnitine biosynthesis pathway GBB's conversion to carnitine and the downstream fat oxidation it enables generates metabolic heat as a byproduct of increased beta-oxidation activity

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This redox reaction triggered by GSH conspicuously reduced the inactivation and efflux of cisplatin and enhanced its chemotherapy toxicity, resulting in considerable inhibition on tumor cells

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