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In healthy adult humans, metabolically active adipose tissue depots with beige-like features were found in the cervical, supraclavicular, axillary, and paravertebral regions (Nedergaard et al., 2007)

doi: 10.1002/9780470720981.ch4 111 ZimmermanSReiterRJ

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Cell Metab 30(5):976986 e973

While previous studies have assessed cardiovascular outcomes in people with T2D and have largely assessed the older generation of GLP-1 RAs, the present study is among the first to examine cardiovascular outcomes in a large US population with T2D and ASCVD and those treated with the newer generation of OW GLP-1 RAs (eg, dulaglutide, semaglutide)

Unusual fatigue that interferes with daily function deserves investigation