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Kidney function: Theres strong evidence that semaglutide helps protect kidney function in people with obesity or diabetes and emerging research that tirzepatide may provide that as well

1 Lillys Phase 2 trial found that starting at 2 mg rather than 4 mg reduced nausea and vomiting during the stepping-up phase, which is why every Phase 3 trial uses a slow stepwise dose schedule

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Shaking creates foam, and foam means air-liquid interfaces where peptide molecules are subjected to surface tension forces that cause denaturation