WO2014052766A1 - Hepatocyte growth factor mimics as therapeutic agents - Google Patents Hepatocyte growth factor mimics as therapeutic agents Download PDF Info Publication number WO2014052766A1 WO2014052766A1 PCT/US2013/062199 US2013062199W WO2014052766A1 WO 2014052766 A1 WO2014052766 A1 WO 2014052766A1 US 2013062199 W US2013062199 W US 2013062199W WO 2014052766 A1 WO2014052766 A1 WO 2014052766A1 Authority WO WIPO (PCT) Prior art keywords hgf dihexa group mimics nle Prior art date Legal status (The legal status is an assumption and is not a legal conclusion
Keywords: G-protein-coupled receptors, GLP-1 receptor agonist, GIP receptor agonist, glucagon receptor agonist, obesity, type 2 diabetes 1
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Moreover, alcohol and acetone have been demonstrated to directly induce keratinocyte proliferation and enhance the mRNA expression of genes associated with cell growth, including 5 integrin, cyclin D1, and the keratinocyte growth factor receptor
Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC, Ingold I, et al