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145 One of the primary ways in which a KD potentially promotes potential anticancer effects is by increasing the levels of -hydroxybutyrate (-HB), which is the most abundant ketone body

In a rat model, co-administration of Wuzhi tabletsan ethanol extract of Schisandra sphenanthera containing schisandrin, schizandrol B, schisantherin A, schisanhenol, and deoxyschizandrinsignificantly altered cyclosporine A blood levels, suggesting sensitivity to CYP3A/P-gp modulation [118, 119], Wuzhi capsules found that Wuzhi tablets influenced cyclophosphamide metabolism, potentially mitigating its nephrotoxic and hepatotoxic effects

Barrea, L

J Biomed Mater Res B Appl Biomater (2022) 110(8):1796805