In REDEFINE 1 (NEJM 2025, n=3,417, 68 weeks), cagrilintide monotherapy at 2.4 mg produced 11.8% mean body-weight reduction versus 2.3% with placebo
Treatment with once-weekly cagrilintide (0.16, 0.30, 0.60, 1.2, 2.4, and 4.5 mg) in combination with semaglutide 2.4 mg for 20 weeks was not associated with an increase in adverse events compared with placebo in combination with semaglutide 2.4 mg, with no unexpected safety or tolerability findings
Timeline expectations are among the most searched questions in this category
10 DeavallD
When paired with vitamin C, the liposomal delivery system ensures that both nutrients are available to the cells at the same time
The work was funded with grants from ISCIIIs Fund for Research in Health Sciences and the Community of Madrid