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Targeted activation of Nrf2 inhibits ROS production, thereby suppressing the proliferation and migration of fibroblast-like synovial cells, which resemble fibroblasts in rheumatoid arthritis [156]

References 1.Allen J., Bradley R.D.2011

Bioactive tripeptides such as GHK-Cu and Lysine-Proline-Valine (KPV), including advanced formulations like KPV incorporated into in situ mucoadhesive hydrogels (KPV@PPP_E), can influence key biological events

Focus on a diet rich in sulfur-containing foods like garlic, onions, and cruciferous vegetables

doi: 10.1089/ars.2013.5802

ACSL4 catalyzes the esterification of free AA and AdA with coenzyme A (CoA) to form PUFA-CoA derivatives (AA-CoA or AdA-CoA) (Liu et al., 2022a)