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Absolute Contraindications Do not use GLP-1 and dual GIP/GLP-1 medications if you have any of the following: A personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2) A history of pancreatitis or symptomatic gastroparesis Severe gastrointestinal disease Pregnant or planning pregnancy Final Thoughts GLP1 and dual GIP/GLP1 receptor are now widely used to help manage type 2 diabetes and obesity

The lower oesophageal sphincter (LOS) consists of a 24 cm zone in the distal end of the oesophagus that has a high resting tone and, assisted by the diaphragmatic sphincter, is largely responsible for the prevention of gastric reflux

They can be received independently or as a booster to your treatment plan

T cells in colorectal cancer: unravelling the function of different T cell subsets in the tumor microenvironment

References 1. 2

Loss of glutamine synthetase in the human epileptogenic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy