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Participants with BMI under 35 had higher dropout rates, sometimes due to perceived excessive weight loss. For participants with BMI 35 (the primary target population for this medication), discontinuation rates were 8.8-12.1%, more comparable to other weight loss medications

The filing comes amid increasing scrutiny of potential vision-related side effects linked to GLP-1 receptor agonists

The Lancet Psychiatry, 13, 327-335.

Semaglutide safely helps patients lose weight and avoid setbacks caused by emotional eating with once-per-week injections

Vitamin B12 supports energy metabolism and may help reduce fatigue for some patients