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Can I use both compounds at the same time

In 2026 Zepbound prescribing information, eructationbelchingwas reported in 4% to 5% of the three dose groups compared with 1% on placebo

This is not unique to GLP-1 therapy

In contrast, a multicenter retrospective cohort study, including a higher-risk population (23% with CKD) reported slower eGFR decline and lower risks of CKD progression and doubling of serum creatinine among SGLT2 inhibitor users compared with GLP-1 receptor agonist users