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Specific findings included increases in B-cell responsiveness and IL-2 receptor-expressing lymphocyte populations

As discussed in the previous sections, obesogenic signalling induces a spectrum of dysfunctional changes in adipose tissue that encompass pathological remodelling of adipose depots via adipocyte hypertrophy, lipid dyshomeostasis, dysregulated secretion of adipokines, namely leptin, and low-grade chronic inflammation [311]

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To overcome this challenge, pharmaceutical scientists have explored several strategies: Absorption enhancers : Chemical agents that temporarily increase the permeability of the gut lining to allow peptide absorption

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