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Consistent with the in vivo results, HU inhibited BAX by upregulating BCL2 expression levels in HG-treated HRMC cells, thereby attenuating apoptosis

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Researchers are interested in this function for its implications in longevity and disease prevention studies

10.1038/s41392-021-00679-0 Signal Transduct Target Ther

Fibroblasts produce growth factors and create the structural framework for skin to build

They are also necessary for the interconversion of amino acids such as the metabolism of histidine to glutamic acid and the interconversion of serine and glycine