Chang JC, Hsu SH, Chen DC
Risks of misuse Improper use of peptides can lead to more significant health concerns: Overuse: Using higher amounts than recommended can lead to hormonal imbalances, such as elevated growth hormone levels, which may cause unwanted side effects like joint discomfort or puffiness
FDA staff's own briefing document, posted publicly ahead of the meeting as part of the docket, proposes that TB-500 (free base) and TB-500 acetate not be added to the list, citing incomplete physicochemical characterization, a lack of evidence of effectiveness for wound healing (including an in-vitro fibroblast study in which TB-500 reportedly did not induce wound healing), and insufficient nonclinical and clinical safety data
Women with endometriosis had significantly lower GLP-1 concentrations in their peritoneal fluid compared to controls, with statistical significance at p = 0.009
Do not freeze dry powder
The workshop needs to meet the D-level clean standard, and the air cleanliness should be controlled so that the number of dust particles 0.5m in each cubic meter of air does not exceed 3,520,000
