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Dehydration occurs frequently due to decreased thirst sensation and reduced caloric intake, leading to orthostatic hypotension when changing positions quickly

Clinical trials for other diseases are ongoing but have not yet obtained definitive results

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Measurable nerve function improvements on objective testing typically require 3 to 6 months of consistent protocol adherence

These variant patterns may help provide context for why some patients experience robust response at standard doses while others require adjustmentthough genetic predisposition alone does not predict exact medication response