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Komatsu M, Takei M, Ishii H, Sato Y

Heterologous expression in vitro unveiled its constitutive activity capable to raise intracellular cAMP levels through Gs (321) and lead to the secretion of GLP-1 and PYY (89)

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SHH has previously been identified as a critical signal for the maintenance and renewal of taste cells, while PLC-2 is a marker involved in sweet, umami, and bitter signaling within type II cells, which may contribute to reduced sensitivity to taste stimuli (107)

The most durable results come from a supervised plan with monitoring, muscle protection, and a maintenance strategy, not a single prescription

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