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Additionally, both LPS and radiation activate death receptors (e.g., Fas/FasL) on cell membranes, initiating caspase-8-mediated cleavage of downstream caspase-3 to execute apoptosis [61-64]

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Reproduction (2002) 123:21726

Mitochondrial-Derived Peptide MOTS-c Ameliorates Spared Nerve Injury-Induced Neuropathic Pain in Mice by Inhibiting Microglia Activation and Neuronal Oxidative Damage in the Spinal Cord via the AMPK Pathway