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The natural polyphenol resveratrol, derivative of trans -stilbene, exerts a wide range of effects including antiproliferative activity via stimulation of both the BECN1-independent autophagy and apoptosis of cancer cells [64]

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rhamnosus GG emerged as the most consistently effective, reducing plasma TMAO in both contexts

Lastly, when comparing children with stage 3 konzo with their unaffected siblings, we found that in addition to GPx3, Zinc-alpha-2-glycoprotein (AZGP1) and Carboxypeptidase B2 (CPB2) were major contributors to group segregation, with CP protein also being identified as being a potential contributor (Fig