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Retained Gastric Contents Studies Multiple studies have consistently demonstrated increased rates of retained gastric contents in patients taking GLP-1 RAs, though with variable magnitude depending on study design and patient populations [32]

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To gain further insight, a non-compartmental PK analysis was performed using gPKPDSim 74 , which revealed a 3.8-fold slower clearance rate (CL) and a 2.4-fold longer mean residence time (MRT) of QMP compared with WT albumin (Supplementary Table 4)

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