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Treatment with 5-amino-1mq upregulates proliferationrelated genes (Ki67, PCNA), promotes cell cycle progression, and improves cell fusion efficiency to form more multinucleated myotubes, achieving functional levels similar to those of young mice.Additionally, 5-amino-1mq inhibits muscle stem cell apoptosis, reduces oxidative stress damage, and maintains stemness

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To validate, intranasal delivery of MSC-derived exosomes reduced extracellular plaque, inflammation, and glial activation in a mouse model of AD

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In the context of GLP-1 receptor agonists, microdosing involves using doses below the standard therapeutic range for diabetes or weight management