including semaglutide branded as Wegovy or Ozempic, and tirzepatide (dual GIP/GLP-1 receptor agonist) branded as Zepbound or Mounjaro, for the management of obesity, type 2 diabetes, and other metabolic conditions increases, so too does the need to assess the advantages and potential downsides of long-term use
A position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases
86 Asp is also a metabolite of the urea cycle, carrying reduction equivalents in the malate-Asp shuttle, providing nitrogen atoms in inosine synthesis, and acting as a hydrogen acceptor in ATP synthesis
A tolerable upper intake level (UL)the amount you can safely take without risk of severe side effectswas never set for it because it has a low potential for toxicity, and the body does not store it in excess (NIH-a, 2021)
Both are used in tissue-repair research but through different pathways
Bucinskaite V, Tolessa T, Pedersen J, et al