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Potential side effects may include injection site irritation and/or redness, temporary fatigue as body adjust to the therapy, mild nausea, headache, water retention, temporary digestive changes Peptide therapy should always be supervised by a qualified medical provider experienced in regenerative medicine and peptide optimization

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However, increased local blood flow from very hot water immediately after injection might theoretically affect the rate of medication absorption , although this has not been specifically studied with Wegovy