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Antifungal Medications These drugs, including ketoconazole or itraconazole, can increase the risk of excess internal bleeding

No metabolic effects on breast-fed newborn/infant are anticipated as insulin glargine is digested into amino acids in the gastrointestinal tract

Duration of action can be about 6-12 hours after onset of effect

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Fertility, pregnancy, and fetal development-specific data are extremely limited, so reproductive use is extrapolated from other human data and animal studies

GLP-1 activation slows gastric emptying, reduces appetite signaling from the gut to the brain, and increases the sensation of fullness after meals