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In this manuscript, we propose that an integrative neurogenomics workflowcombining multi-omic phenotypeoriented whole-exome sequencing, biologically-oriented common variant burden profiling, biochemical markers, functional metagenomic data, and multidisciplinary clinical interpretationcan generate testable, personalized diagnostic and therapeutic hypotheses in neurodegenerative disorders

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Glutathione in Brain: Overview of Its Conformations, Functions, Biochemical Characteristics, Quantitation and Potential Role in Brain Health

Spiking blood simultaneously with extraction buffer (Sample Type 2) resulted in improved recoveries98% for NAD + , 85% for NADH (with only 10% converting to NAD + ), 95% for NADP + and 82% for NADPH