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N Engl J Med 375:311322 Hollander P, Gupta AK, Plodkowski R et al (2013) Effects of naltrexone sustained-release/bupropion sustained-release combination therapy on body weight and glycemic parameters in overweight and obese patients with type 2 diabetes

These peptides act on pathways related to cell migration, blood vessel formation, and soft tissue healing

Specifically, the study found the class of drugs compared with bupropion-naltrexone were linked with an increased risk of pancreatitis, bowel obstruction, and gastroparesis but not biliary disease

I am not sure how rigorous theyre going to be in terms of needed justification, said Dr

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