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[DOI] [PubMed] [Google Scholar] 50.Parmar PA, Chow LW, St-Pierre JP, Horejs CM, Peng YY, Werkmeister JA, Ramshaw JA, Stevens MM
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They recruit immune cells, produce inflammatory cytokines, create local estrogen signaling, and contribute to scar tissue formation and adhesions
Engineering peptide stability to generate sustained in vivo GLP-1R activation in vivo Cleavage after position W25 was also detected during production for some of our initial GLP-1 analogue peptide-antibody fusions and we hypothesized that W25 would be particularly labile